Quality versus Risk-of-Bias assessment in clinical research

Assessment of internal validity safeguards implemented by researchers has been used to examine the potential reliability evidence generated within a study. These protect against systematic error, and such an assessment traditionally called quality assessment. When results are translated through some empirical construct risk bias, this termed bias The latter gained popularity is commonly interchangeably with term This key concept paper clarifies differences between these assessments how they may be interpreted when assessing clinical for validity.